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Long-Term Outcomes Following Hepatic Resection and Radiofrequency Ablation of Colorectal Liver Metastases

Recently some have called for randomized controlled trials comparing RFA to hepatic resection, particularly for patients with only a few small metastases. The objectives were to compare local recurrence and survival following RFA and hepatic resection for colorectal liver metastases. This was a retr...

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Detalles Bibliográficos
Autores principales: McKay, Andrew, Fradette, Katherine, Lipschitz, Jeremy
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817867/
https://www.ncbi.nlm.nih.gov/pubmed/20148084
http://dx.doi.org/10.1155/2009/346863
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author McKay, Andrew
Fradette, Katherine
Lipschitz, Jeremy
author_facet McKay, Andrew
Fradette, Katherine
Lipschitz, Jeremy
author_sort McKay, Andrew
collection PubMed
description Recently some have called for randomized controlled trials comparing RFA to hepatic resection, particularly for patients with only a few small metastases. The objectives were to compare local recurrence and survival following RFA and hepatic resection for colorectal liver metastases. This was a retrospective review of open RFA and hepatic resection for colorectal liver metastases between January 1998 and May 2007. All patients who had RFA were considered to have unresectable disease. 58 patients had hepatic resection and 43 had RFA. A 5-year survival after resection was 43% compared to 23% after RFA. For patients with solitary lesions, a 5-year survival was 48% after resection and 15% after RFA. Sixty percent of patients suffered local recurrences after RFA compared to 7% after hepatic resection. RFA is inferior to resection. The results observed in this study support the consensus that RFA cannot be considered an equivalent procedure to hepatic resection.
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spelling pubmed-28178672010-02-10 Long-Term Outcomes Following Hepatic Resection and Radiofrequency Ablation of Colorectal Liver Metastases McKay, Andrew Fradette, Katherine Lipschitz, Jeremy HPB Surg Research Article Recently some have called for randomized controlled trials comparing RFA to hepatic resection, particularly for patients with only a few small metastases. The objectives were to compare local recurrence and survival following RFA and hepatic resection for colorectal liver metastases. This was a retrospective review of open RFA and hepatic resection for colorectal liver metastases between January 1998 and May 2007. All patients who had RFA were considered to have unresectable disease. 58 patients had hepatic resection and 43 had RFA. A 5-year survival after resection was 43% compared to 23% after RFA. For patients with solitary lesions, a 5-year survival was 48% after resection and 15% after RFA. Sixty percent of patients suffered local recurrences after RFA compared to 7% after hepatic resection. RFA is inferior to resection. The results observed in this study support the consensus that RFA cannot be considered an equivalent procedure to hepatic resection. Hindawi Publishing Corporation 2009 2010-02-01 /pmc/articles/PMC2817867/ /pubmed/20148084 http://dx.doi.org/10.1155/2009/346863 Text en Copyright © 2009 Andrew McKay et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
McKay, Andrew
Fradette, Katherine
Lipschitz, Jeremy
Long-Term Outcomes Following Hepatic Resection and Radiofrequency Ablation of Colorectal Liver Metastases
title Long-Term Outcomes Following Hepatic Resection and Radiofrequency Ablation of Colorectal Liver Metastases
title_full Long-Term Outcomes Following Hepatic Resection and Radiofrequency Ablation of Colorectal Liver Metastases
title_fullStr Long-Term Outcomes Following Hepatic Resection and Radiofrequency Ablation of Colorectal Liver Metastases
title_full_unstemmed Long-Term Outcomes Following Hepatic Resection and Radiofrequency Ablation of Colorectal Liver Metastases
title_short Long-Term Outcomes Following Hepatic Resection and Radiofrequency Ablation of Colorectal Liver Metastases
title_sort long-term outcomes following hepatic resection and radiofrequency ablation of colorectal liver metastases
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817867/
https://www.ncbi.nlm.nih.gov/pubmed/20148084
http://dx.doi.org/10.1155/2009/346863
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