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Irreversibility of mitotic exit is the consequence of systems level feedback
The eukaryotic cell cycle comprises an ordered series of events, orchestrated by the activity of cyclin-dependent kinases (Cdks), leading from chromosome replication during S-phase to their segregation in mitosis. The unidirectionality of cell cycle transitions is fundamental for successful completi...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817895/ https://www.ncbi.nlm.nih.gov/pubmed/19387440 http://dx.doi.org/10.1038/nature07984 |