ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis

The viviparous Great Barrier Reef sponge Luffariella variabilis (Poléjaeff 1884) contains a range of secondary metabolites, including manoalide (1) and manoalide monoacetate (3). ESI (+) FTICR-MS accurate mass determination has, for the first time, been used to detected the presence of 3 only in an...

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Autores principales: Motti, Cherie A., Ettinger-Epstein, Piers, Willis, Richard H., Tapiolas, Dianne M.
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817929/
https://www.ncbi.nlm.nih.gov/pubmed/20161977
http://dx.doi.org/10.3390/md8010190
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author Motti, Cherie A.
Ettinger-Epstein, Piers
Willis, Richard H.
Tapiolas, Dianne M.
author_facet Motti, Cherie A.
Ettinger-Epstein, Piers
Willis, Richard H.
Tapiolas, Dianne M.
author_sort Motti, Cherie A.
collection PubMed
description The viviparous Great Barrier Reef sponge Luffariella variabilis (Poléjaeff 1884) contains a range of secondary metabolites, including manoalide (1) and manoalide monoacetate (3). ESI (+) FTICR-MS accurate mass determination has, for the first time, been used to detected the presence of 3 only in an organic extract of a single L. variabilis larva showing that the parentally produced 3 is sequestered in the larva. As 3 has previously been shown to have antibacterial and quorum sensing inhibition activity, and readily converts to 1, which also exhibits similar activity, it may provide a chemical defence against predation and microbial attack.
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spelling pubmed-28179292010-02-16 ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis Motti, Cherie A. Ettinger-Epstein, Piers Willis, Richard H. Tapiolas, Dianne M. Mar Drugs Article The viviparous Great Barrier Reef sponge Luffariella variabilis (Poléjaeff 1884) contains a range of secondary metabolites, including manoalide (1) and manoalide monoacetate (3). ESI (+) FTICR-MS accurate mass determination has, for the first time, been used to detected the presence of 3 only in an organic extract of a single L. variabilis larva showing that the parentally produced 3 is sequestered in the larva. As 3 has previously been shown to have antibacterial and quorum sensing inhibition activity, and readily converts to 1, which also exhibits similar activity, it may provide a chemical defence against predation and microbial attack. Molecular Diversity Preservation International 2010-01-22 /pmc/articles/PMC2817929/ /pubmed/20161977 http://dx.doi.org/10.3390/md8010190 Text en © 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Motti, Cherie A.
Ettinger-Epstein, Piers
Willis, Richard H.
Tapiolas, Dianne M.
ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis
title ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis
title_full ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis
title_fullStr ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis
title_full_unstemmed ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis
title_short ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis
title_sort esi fticr-ms analysis of larvae from the marine sponge luffariella variabilis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817929/
https://www.ncbi.nlm.nih.gov/pubmed/20161977
http://dx.doi.org/10.3390/md8010190
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