Cargando…
MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8
Senescence is a cellular program that irreversibly arrests the proliferation of damaged cells and induces the secretion of the inflammatory mediators IL- 6 and IL-8 which are part of a larger senescence associated secretory phenotype (SASP). We screened quiescent and senescent human fibroblasts for...
Autores principales: | Bhaumik, Dipa, Scott, Gary K., Schokrpur, Shiruyeh, Patil, Christopher K., Orjalo, Arturo V., Rodier, Francis, Lithgow, Gordon J., Campisi, Judith |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818025/ https://www.ncbi.nlm.nih.gov/pubmed/20148189 |
Ejemplares similares
-
Two faces of p53: aging and tumor suppression
por: Rodier, Francis, et al.
Publicado: (2007) -
Four faces of cellular senescence
por: Rodier, Francis, et al.
Publicado: (2011) -
Plasma microRNA-21, microRNA-146a and IL-13 expression in asthmatic
children
por: Hammad Mahmoud Hammad, Reham, et al.
Publicado: (2018) -
Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype
por: Wiley, Christopher D., et al.
Publicado: (2018) -
Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
por: Coppé, Jean-Philippe, et al.
Publicado: (2008)