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MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cells
BACKGROUND: Cancer cells utilize a variety of mechanisms to evade immune detection and attack. Effective immune detection largely relies on the formation of an immune synapse which requires close contact between immune cells and their targets. Here, we show that MUC16, a heavily glycosylated 3-5 mil...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818693/ https://www.ncbi.nlm.nih.gov/pubmed/20089172 http://dx.doi.org/10.1186/1476-4598-9-11 |