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Smoothened as a new therapeutic target for human osteosarcoma

BACKGROUND: The Hedgehog signaling pathway functions as an organizer in embryonic development. Recent studies have demonstrated constitutive activation of Hedgehog pathway in various types of malignancies. However, it remains unclear how Hedgehog pathway is involved in the pathogenesis of osteosarco...

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Detalles Bibliográficos
Autores principales:	Hirotsu, Masataka, Setoguchi, Takao, Sasaki, Hiromi, Matsunoshita, Yukihiro, Gao, Hui, Nagao, Hiroko, Kunigou, Osamu, Komiya, Setsuro
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818696/ https://www.ncbi.nlm.nih.gov/pubmed/20067614 http://dx.doi.org/10.1186/1476-4598-9-5

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