Gab2 Promotes Hematopoietic Stem Cell Maintenance and Self-Renewal Synergistically with STAT5

BACKGROUND: Grb2-associated binding (Gab) adapter proteins play major roles in coordinating signaling downstream of hematopoietic cytokine receptors. In hematopoietic cells, Gab2 can modulate phosphatidylinositol–3 kinase and mitogen associated protein kinase activities and regulate the long-term mu...

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Detalles Bibliográficos
Autores principales: Li, Geqiang, Wang, Zhengqi, Miskimen, Kristy L., Zhang, Yi, Tse, William, Bunting, Kevin D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818849/
https://www.ncbi.nlm.nih.gov/pubmed/20161778
http://dx.doi.org/10.1371/journal.pone.0009152

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