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Luteolin triggers global changes in the microglial transcriptome leading to a unique anti-inflammatory and neuroprotective phenotype
BACKGROUND: Luteolin, a plant derived flavonoid, exerts a variety of pharmacological activities and anti-oxidant properties associated with its capacity to scavenge oxygen and nitrogen species. Luteolin also shows potent anti-inflammatory activities by inhibiting nuclear factor kappa B (NFkB) signal...
Autores principales: | Dirscherl, Konstantin, Karlstetter, Marcus, Ebert, Stefanie, Kraus, Dominik, Hlawatsch, Julia, Walczak, Yana, Moehle, Christoph, Fuchshofer, Rudolf, Langmann, Thomas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819254/ https://www.ncbi.nlm.nih.gov/pubmed/20074346 http://dx.doi.org/10.1186/1742-2094-7-3 |
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