The Ca(2+ )activated SK3 channel is expressed in microglia in the rat striatum and contributes to microglia-mediated neurotoxicity in vitro

BACKGROUND: Small-conductance Ca(2+ )activated K(+ )channels are expressed in the CNS, where KCNN2/SK2/KCa2.2 and KCNN3/SK3/KCa2.3 help shape the electrical activity of some neurons. The SK3 channel is considered a potential therapeutic target for diseases and disorders involving neuron hyper-excita...

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Detalles Bibliográficos
Autores principales: Schlichter, Lyanne C, Kaushal, Vikas, Moxon-Emre, Iska, Sivagnanam, Vishanthan, Vincent, Catherine
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819255/
https://www.ncbi.nlm.nih.gov/pubmed/20074365
http://dx.doi.org/10.1186/1742-2094-7-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819255/
https://www.ncbi.nlm.nih.gov/pubmed/20074365
http://dx.doi.org/10.1186/1742-2094-7-4

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