A multicenter investigation of OPTI-FREE(®) RepleniSH(®) multi-purpose disinfecting solution impact on soft contact lens patient comfort

OBJECTIVE: Demonstrate that successful soft contact lens wearers using competitive multipurpose solutions report improvement in comfort with OPTI-FREE(®) RepleniSH(®) Multi-Purpose Disinfecting Solution (MPDS). METHODS: This 30-day, multicentered, open-label study enrolled 109 eligible soft contact lens wearers using COMPLETE(®) Multi-Purpose Solution (MPS) Easy Rub(®) or ReNu MultiPlus(®) MPS. The test solution (OPTI-FREE(®) RepleniSH(®) MPDS) was dispensed for use in place of habitual care solutions. Subjects assessed their experience with their habitual solution (baseline) and the test solution (Day 30) using Likert-style questions. Contact lens acuity and biomicroscopy findings were recorded at each visit. RESULTS: The test solution was associated with a statistically significant improvement in instillation comfort (P = 0.02), end of day comfort (P < 0.0001), clear vision (P < 0.0001) and overall satisfaction (P < 0.001). Subjects reported the test solution enhanced their overall lens-wearing experience more effectively than their previous solution (P < 0.0001) and that they would continue test solution use after the study (P < 0.0001). CONCLUSIONS: The test solution was effective at improving comfort and overall contact lens experience compared to COMPLETE(®) MPS Easy Rub(®) or ReNu MultiPlus(®) MPS in successful contact lens wearers. These results indicate that changing contact lens care solutions, even in successful lens wearers, may improve comfort and overall lens-wearing experience.