To Match or Not to Match in Epidemiological Studies—Same Outcome but Less Power

This study aimed to analyze the possible resemblance or difference in outcome in a case-control study of quality of life for IBS patients compared to controls free from the disease, when a matching procedure for age and sex was applied for the control group compared to when all participating subject...

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Detalles Bibliográficos
Autores principales: Faresjö, Tomas, Faresjö, Åshild
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819792/
https://www.ncbi.nlm.nih.gov/pubmed/20195449
http://dx.doi.org/10.3390/ijerph7010325
Descripción
Sumario:This study aimed to analyze the possible resemblance or difference in outcome in a case-control study of quality of life for IBS patients compared to controls free from the disease, when a matching procedure for age and sex was applied for the control group compared to when all participating subjects were included in the control group. The main result was that almost the same and identical results were found irrespective of whether matching or not matching was applied in this epidemiological case-control study. The matching procedure however, slightly diminished the statistical power of the results.

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