Cargando…

17β-Estradiol inhibits matrix metalloproteinase-2 transcription via MAP kinase in fibroblasts

AIMS: Female sex and sex hormones contribute to cardiac remodelling. 17β-estradiol (E2) is involved in the modulation of extracellular matrix composition and function. Here, we analysed the effect of E2 on matrix metalloproteinase (MMP)-2 gene expression and studied the underlying molecular mechanis...

Descripción completa

Detalles Bibliográficos
Autores principales: Mahmoodzadeh, Shokoufeh, Dworatzek, Elke, Fritschka, Stephan, Pham, Thi Hang, Regitz-Zagrosek, Vera
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819834/
https://www.ncbi.nlm.nih.gov/pubmed/19861308
http://dx.doi.org/10.1093/cvr/cvp350