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17β-Estradiol inhibits matrix metalloproteinase-2 transcription via MAP kinase in fibroblasts

AIMS: Female sex and sex hormones contribute to cardiac remodelling. 17β-estradiol (E2) is involved in the modulation of extracellular matrix composition and function. Here, we analysed the effect of E2 on matrix metalloproteinase (MMP)-2 gene expression and studied the underlying molecular mechanis...

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Detalles Bibliográficos
Autores principales:	Mahmoodzadeh, Shokoufeh, Dworatzek, Elke, Fritschka, Stephan, Pham, Thi Hang, Regitz-Zagrosek, Vera
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819834/ https://www.ncbi.nlm.nih.gov/pubmed/19861308 http://dx.doi.org/10.1093/cvr/cvp350

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