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Avian Bornaviruses in Psittacine Birds from Europe and Australia with Proventricular Dilatation Disease
To determine whether avian bornaviruses (ABVs) were a factor in proventricular dilatation disease (PDD), we used immunohistochemistry, reverse transcription–PCR, and nucleotide sequence analysis to examine paraffin wax–embedded or frozen tissue samples of 31 psittacine birds with this disease. PDD i...
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Formato: | Texto |
Lenguaje: | English |
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Centers for Disease Control and Prevention
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819881/ https://www.ncbi.nlm.nih.gov/pubmed/19788814 http://dx.doi.org/10.3201/eid1509.090353 |
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author | Weissenböck, Herbert Bakonyi, Tamás Sekulin, Karin Ehrensperger, Felix Doneley, Robert J.T. Dürrwald, Ralf Hoop, Richard Erdélyi, Károly Gál, János Kolodziejek, Jolanta Nowotny, Norbert |
author_facet | Weissenböck, Herbert Bakonyi, Tamás Sekulin, Karin Ehrensperger, Felix Doneley, Robert J.T. Dürrwald, Ralf Hoop, Richard Erdélyi, Károly Gál, János Kolodziejek, Jolanta Nowotny, Norbert |
author_sort | Weissenböck, Herbert |
collection | PubMed |
description | To determine whether avian bornaviruses (ABVs) were a factor in proventricular dilatation disease (PDD), we used immunohistochemistry, reverse transcription–PCR, and nucleotide sequence analysis to examine paraffin wax–embedded or frozen tissue samples of 31 psittacine birds with this disease. PDD is a fatal disease of psittacine birds associated with nonsuppurative encephalitis and ganglioneuritis of the upper intestinal tract. Tissue samples had been collected from 1999 through 2008 in Austria, Switzerland, Hungary, and Australia. Immunohistochemical demonstration of viral antigen within the brain and vegetative nerve system of the gastrointestinal tract provides strong evidence for a causative role of ABVs in this condition. Partial sequences of nucleoprotein (p40) and matrix protein (gp18) genes showed that virus in most of our cases belonged to the ABV-2 and ABV-4 groups among the 5 genogroups described so far. Viral sequences of 2 birds did not match any of the described sequences and clustered together in a new branch termed ABV-6. |
format | Text |
id | pubmed-2819881 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Centers for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-28198812010-02-23 Avian Bornaviruses in Psittacine Birds from Europe and Australia with Proventricular Dilatation Disease Weissenböck, Herbert Bakonyi, Tamás Sekulin, Karin Ehrensperger, Felix Doneley, Robert J.T. Dürrwald, Ralf Hoop, Richard Erdélyi, Károly Gál, János Kolodziejek, Jolanta Nowotny, Norbert Emerg Infect Dis Research To determine whether avian bornaviruses (ABVs) were a factor in proventricular dilatation disease (PDD), we used immunohistochemistry, reverse transcription–PCR, and nucleotide sequence analysis to examine paraffin wax–embedded or frozen tissue samples of 31 psittacine birds with this disease. PDD is a fatal disease of psittacine birds associated with nonsuppurative encephalitis and ganglioneuritis of the upper intestinal tract. Tissue samples had been collected from 1999 through 2008 in Austria, Switzerland, Hungary, and Australia. Immunohistochemical demonstration of viral antigen within the brain and vegetative nerve system of the gastrointestinal tract provides strong evidence for a causative role of ABVs in this condition. Partial sequences of nucleoprotein (p40) and matrix protein (gp18) genes showed that virus in most of our cases belonged to the ABV-2 and ABV-4 groups among the 5 genogroups described so far. Viral sequences of 2 birds did not match any of the described sequences and clustered together in a new branch termed ABV-6. Centers for Disease Control and Prevention 2009-09 /pmc/articles/PMC2819881/ /pubmed/19788814 http://dx.doi.org/10.3201/eid1509.090353 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
spellingShingle | Research Weissenböck, Herbert Bakonyi, Tamás Sekulin, Karin Ehrensperger, Felix Doneley, Robert J.T. Dürrwald, Ralf Hoop, Richard Erdélyi, Károly Gál, János Kolodziejek, Jolanta Nowotny, Norbert Avian Bornaviruses in Psittacine Birds from Europe and Australia with Proventricular Dilatation Disease |
title | Avian Bornaviruses in Psittacine Birds from Europe and Australia with Proventricular Dilatation Disease |
title_full | Avian Bornaviruses in Psittacine Birds from Europe and Australia with Proventricular Dilatation Disease |
title_fullStr | Avian Bornaviruses in Psittacine Birds from Europe and Australia with Proventricular Dilatation Disease |
title_full_unstemmed | Avian Bornaviruses in Psittacine Birds from Europe and Australia with Proventricular Dilatation Disease |
title_short | Avian Bornaviruses in Psittacine Birds from Europe and Australia with Proventricular Dilatation Disease |
title_sort | avian bornaviruses in psittacine birds from europe and australia with proventricular dilatation disease |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819881/ https://www.ncbi.nlm.nih.gov/pubmed/19788814 http://dx.doi.org/10.3201/eid1509.090353 |
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