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Surface engineering of macrophages with nanoparticles to generate a cell–nanoparticle hybrid vehicle for hypoxia-targeted drug delivery

Tumors frequently contain hypoxic regions that result from a shortage of oxygen due to poorly organized tumor vasculature. Cancer cells in these areas are resistant to radiation- and chemotherapy, limiting the treatment efficacy. Macrophages have inherent hypoxia-targeting ability and hold great adv...

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Detalles Bibliográficos
Autores principales: Holden, Christopher A, Yuan, Quan, Yeudall, W Andrew, Lebman, Deborah A, Yang, Hu
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819902/
https://www.ncbi.nlm.nih.gov/pubmed/20161985

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