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Evidence that Gag facilitates HIV-1 envelope association both in GPI-enriched plasma membrane and detergent resistant membranes and facilitates envelope incorporation onto virions in primary CD4(+ )T cells

HIV-1 particle assembly mediated by viral Gag protein occurs predominantly at plasma membrane. While colocalization of HIV-1 envelope with lipid rich microenvironment have been shown in T cells, the significance of viral proteins modulating envelope association in such microdomains in plasma membran...

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Detalles Bibliográficos
Autores principales: Patil, Ajit, Gautam, Archana, Bhattacharya, Jayanta
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820015/
https://www.ncbi.nlm.nih.gov/pubmed/20064199
http://dx.doi.org/10.1186/1743-422X-7-3