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Potent Anti-Inflammatory Activity of Novel Microtubule-Modulating Brominated Noscapine Analogs
Noscapine, a plant-derived, non-toxic, over-the-counter antitussive alkaloid has tubulin-binding properties. Based upon the structural resemblance of noscapine to colchicine, a tubulin-binding anti-inflammatory drug, noscapine and its semi-synthetic brominated analogs were examined for in vitro anti...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820095/ https://www.ncbi.nlm.nih.gov/pubmed/20161797 http://dx.doi.org/10.1371/journal.pone.0009165 |