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Pro-angiogenic effect of IFNγ is dependent on the PI3K/mTOR/translational pathway in human retinal pigmented epithelial cells
PURPOSE: To investigate the molecular signaling pathway of Interferon gamma (IFNγ) contributing to angiogenesis in retinal pigmented epithelial (RPE) cells and the role of Phosphoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) in this process. METHODS: Human adult and fetal RPE cells...
Autores principales: | Liu, Baoying, Faia, Lisa, Hu, Mengjun, Nussenblatt, Robert B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820105/ https://www.ncbi.nlm.nih.gov/pubmed/20157617 |
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