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Bacterial nitric oxide detoxification prevents host cell S-nitrosothiol formation: a novel mechanism of bacterial pathogenesis
S-nitrosylation is an important mediator of multiple nitric oxide-dependent biological processes, including eukaryotic cellular events such as macrophage apoptosis and proinflammatory signaling. Many pathogenic bacteria possess NO detoxification mechanisms, such as the nitric oxide reductase (NorB)...
Autores principales: | Laver, Jay R., Stevanin, Tânia M., Messenger, Sarah L., Lunn, Amy Dehn, Lee, Margaret E., Moir, James W. B., Poole, Robert K., Read, Robert C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Federation of American Societies for Experimental Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820398/ https://www.ncbi.nlm.nih.gov/pubmed/19720623 http://dx.doi.org/10.1096/fj.08-128330 |
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