Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase

BACKGROUND: T-cell protein tyrosine phosphatase (TCPTP/TC45) is a ubiquitously expressed intra-cellular non-receptor protein tyrosine phosphatase involved in the negative regulation of several cancer relevant cellular signalling pathways. We have previously shown that interaction between the α-cytop...

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Detalles Bibliográficos
Autores principales: Mattila, Elina, Marttila, Heidi, Sahlberg, Niko, Kohonen, Pekka, Tähtinen, Siri, Halonen, Pasi, Perälä, Merja, Ivaska, Johanna
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820462/
https://www.ncbi.nlm.nih.gov/pubmed/20055993
http://dx.doi.org/10.1186/1471-2407-10-7

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