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Enhancing Survival of Mouse Oocytes Following Chemotherapy or Aging by Targeting Bax and Rad51

BACKGROUND: Therapeutic approaches to preserve fertility in females undergoing cancer treatments are currently ineffective. This is partly due to limited knowledge of the molecular mechanisms that injured germ cells elicit to repair damage and survive or to abort repair and activate biochemical path...

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Detalles Bibliográficos
Autores principales: Kujjo, Loro L., Laine, Tiina, Pereira, Ricardo J. G., Kagawa, Wataru, Kurumizaka, Hitoshi, Yokoyama, Shigeyuki, Perez, Gloria I.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820548/
https://www.ncbi.nlm.nih.gov/pubmed/20169201
http://dx.doi.org/10.1371/journal.pone.0009204