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In vivo selection of human embryonic stem cell-derived cells expressing methotrexate-resistant dihydrofolate reductase
Human embryonic stem cells (hESCs) provide a novel source of hematopoietic and other cell populations suitable for gene therapy applications. Preclinical studies to evaluate engraftment of hESC-derived hematopoietic cells transplanted into immunodeficient mice demonstrate only limited repopulation....
Autores principales: | Gori, Jennifer L., Tian, Xinghui, Swanson, Debra, Gunther, Roland, Shultz, Leonard D., McIvor, R. Scott, Kaufman, Dan S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820606/ https://www.ncbi.nlm.nih.gov/pubmed/19829316 http://dx.doi.org/10.1038/gt.2009.131 |
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