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Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of d-Amino Acid Deacylase

d-tyrosyl-tRNA(Tyr) deacylase (DTD) is an editing enzyme that removes d-amino acids from mischarged tRNAs. We describe an in-depth analysis of the malaria parasite Plasmodium falciparum DTD here. Our data provide structural insights into DTD complexes with adenosine and d-amino acids. Bound adenosin...

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Detalles Bibliográficos
Autores principales:	Bhatt, Tarun Kumar, Yogavel, Manickam, Wydau, Sandra, Berwal, Ritu, Sharma, Amit
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2010
Materias:	Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820817/ https://www.ncbi.nlm.nih.gov/pubmed/20007323 http://dx.doi.org/10.1074/jbc.M109.038562

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