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A Review on the Effects of Supercritical Carbon Dioxide on Enzyme Activity

Different types of enzymes such as lipases, several phosphatases, dehydrogenases, oxidases, amylases and others are well suited for the reactions in SC-CO(2). The stability and the activity of enzymes exposed to carbon dioxide under high pressure depend on enzyme species, water content in the soluti...

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Detalles Bibliográficos
Autores principales: Wimmer, Zdeněk, Zarevúcka, Marie
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821001/
https://www.ncbi.nlm.nih.gov/pubmed/20162013
http://dx.doi.org/10.3390/ijms11010233
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author Wimmer, Zdeněk
Zarevúcka, Marie
author_facet Wimmer, Zdeněk
Zarevúcka, Marie
author_sort Wimmer, Zdeněk
collection PubMed
description Different types of enzymes such as lipases, several phosphatases, dehydrogenases, oxidases, amylases and others are well suited for the reactions in SC-CO(2). The stability and the activity of enzymes exposed to carbon dioxide under high pressure depend on enzyme species, water content in the solution and on the pressure and temperature of the reaction system. The three-dimensional structure of enzymes may be significantly altered under extreme conditions, causing their denaturation and consequent loss of activity. If the conditions are less adverse, the protein structure may be largely retained. Minor structural changes may induce an alternative active protein state with altered enzyme activity, specificity and stability.
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spelling pubmed-28210012010-02-16 A Review on the Effects of Supercritical Carbon Dioxide on Enzyme Activity Wimmer, Zdeněk Zarevúcka, Marie Int J Mol Sci Review Different types of enzymes such as lipases, several phosphatases, dehydrogenases, oxidases, amylases and others are well suited for the reactions in SC-CO(2). The stability and the activity of enzymes exposed to carbon dioxide under high pressure depend on enzyme species, water content in the solution and on the pressure and temperature of the reaction system. The three-dimensional structure of enzymes may be significantly altered under extreme conditions, causing their denaturation and consequent loss of activity. If the conditions are less adverse, the protein structure may be largely retained. Minor structural changes may induce an alternative active protein state with altered enzyme activity, specificity and stability. Molecular Diversity Preservation International (MDPI) 2010-01-19 /pmc/articles/PMC2821001/ /pubmed/20162013 http://dx.doi.org/10.3390/ijms11010233 Text en © 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Wimmer, Zdeněk
Zarevúcka, Marie
A Review on the Effects of Supercritical Carbon Dioxide on Enzyme Activity
title A Review on the Effects of Supercritical Carbon Dioxide on Enzyme Activity
title_full A Review on the Effects of Supercritical Carbon Dioxide on Enzyme Activity
title_fullStr A Review on the Effects of Supercritical Carbon Dioxide on Enzyme Activity
title_full_unstemmed A Review on the Effects of Supercritical Carbon Dioxide on Enzyme Activity
title_short A Review on the Effects of Supercritical Carbon Dioxide on Enzyme Activity
title_sort review on the effects of supercritical carbon dioxide on enzyme activity
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821001/
https://www.ncbi.nlm.nih.gov/pubmed/20162013
http://dx.doi.org/10.3390/ijms11010233
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