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Effect of Childhood Trauma on Adult Depression and Neuroendocrine Function: Sex-Specific Moderation by CRH Receptor 1 Gene

Variations of the corticotropin-releasing hormone receptor 1 (CRHR1) gene appear to moderate the development of depression after childhood trauma. Depression more frequently affects women than men. We examined sex differences in the effects of the CRHR1 gene on the relationship between childhood tra...

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Detalles Bibliográficos
Autores principales:	Heim, Christine, Bradley, Bekh, Mletzko, Tanja C., Deveau, Todd C., Musselman, Dominique L., Nemeroff, Charles B., Ressler, Kerry J., Binder, Elisabeth B.
Formato:	Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2009
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821197/ https://www.ncbi.nlm.nih.gov/pubmed/20161813 http://dx.doi.org/10.3389/neuro.08.041.2009

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