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Epithelial-mesenchymal transition in primary human bronchial epithelial cells is Smad-dependent and enhanced by fibronectin and TNF-α

BACKGROUND: Defective epithelial repair, excess fibroblasts and myofibroblasts, collagen overproduction and fibrosis occur in a number of respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD) and pulmonary fibrosis. Pathological conversion of epithelial cells into fibrobl...

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Detalles Bibliográficos
Autores principales:	Câmara, Joana, Jarai, Gabor
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821296/ https://www.ncbi.nlm.nih.gov/pubmed/20051102 http://dx.doi.org/10.1186/1755-1536-3-2

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