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Differences in the epigenetic and reprogramming properties of pluripotent and extra-embryonic stem cells implicate chromatin remodelling as an important early event in the developing mouse embryo

BACKGROUND: During early mouse development, two extra-embryonic lineages form alongside the future embryo: the trophectoderm (TE) and the primitive endoderm (PrE). Epigenetic changes known to take place during these early stages include changes in DNA methylation and modified histones, as well as dy...

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Detalles Bibliográficos
Autores principales: Santos, Joana, Filipe Pereira, C, Di-Gregorio, Aida, Spruce, Thomas, Alder, Olivia, Rodriguez, Tristan, Azuara, Véronique, Merkenschlager, Matthias, Fisher, Amanda G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821315/
https://www.ncbi.nlm.nih.gov/pubmed/20157423
http://dx.doi.org/10.1186/1756-8935-3-1