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Diagnostic Strategies for Postmenopausal Bleeding

Postmenopausal bleeding (PMB) is a common clinical problem. Patients with PMB have 10%–15% chance of having endometrial carcinoma and therefore the diagnostic workup is aimed at excluding malignancy. Patient characteristics can alter the probability of having endometrial carcinoma in patients with P...

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Detalles Bibliográficos
Autores principales: Breijer, M. C., Timmermans, A., van Doorn, H. C., Mol, B. W. J., Opmeer, B. C.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821624/
https://www.ncbi.nlm.nih.gov/pubmed/20169169
http://dx.doi.org/10.1155/2010/850812
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author Breijer, M. C.
Timmermans, A.
van Doorn, H. C.
Mol, B. W. J.
Opmeer, B. C.
author_facet Breijer, M. C.
Timmermans, A.
van Doorn, H. C.
Mol, B. W. J.
Opmeer, B. C.
author_sort Breijer, M. C.
collection PubMed
description Postmenopausal bleeding (PMB) is a common clinical problem. Patients with PMB have 10%–15% chance of having endometrial carcinoma and therefore the diagnostic workup is aimed at excluding malignancy. Patient characteristics can alter the probability of having endometrial carcinoma in patients with PMB; in certain groups of patients the incidence has been reported to be as high as 29%. Transvaginal sonography (TVS) is used as a first step in the diagnostic workup, but different authors have come to different conclusions assessing the accuracy of TVS for excluding endometrial carcinoma. Diagnostic procedures obtaining material for histological assessment (e.g., dilatation and curettage, hysteroscopy, and endometrial biopsy) can be more accurate but are also more invasive. The best diagnostic strategy for diagnosing endometrial carcinoma in patients with PMB still remains controversial. Future research should be focussed on achieving a higher accuracy of different diagnostic strategies.
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spelling pubmed-28216242010-02-18 Diagnostic Strategies for Postmenopausal Bleeding Breijer, M. C. Timmermans, A. van Doorn, H. C. Mol, B. W. J. Opmeer, B. C. Obstet Gynecol Int Review Article Postmenopausal bleeding (PMB) is a common clinical problem. Patients with PMB have 10%–15% chance of having endometrial carcinoma and therefore the diagnostic workup is aimed at excluding malignancy. Patient characteristics can alter the probability of having endometrial carcinoma in patients with PMB; in certain groups of patients the incidence has been reported to be as high as 29%. Transvaginal sonography (TVS) is used as a first step in the diagnostic workup, but different authors have come to different conclusions assessing the accuracy of TVS for excluding endometrial carcinoma. Diagnostic procedures obtaining material for histological assessment (e.g., dilatation and curettage, hysteroscopy, and endometrial biopsy) can be more accurate but are also more invasive. The best diagnostic strategy for diagnosing endometrial carcinoma in patients with PMB still remains controversial. Future research should be focussed on achieving a higher accuracy of different diagnostic strategies. Hindawi Publishing Corporation 2010 2010-02-04 /pmc/articles/PMC2821624/ /pubmed/20169169 http://dx.doi.org/10.1155/2010/850812 Text en Copyright © 2010 M. C. Breijer et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Breijer, M. C.
Timmermans, A.
van Doorn, H. C.
Mol, B. W. J.
Opmeer, B. C.
Diagnostic Strategies for Postmenopausal Bleeding
title Diagnostic Strategies for Postmenopausal Bleeding
title_full Diagnostic Strategies for Postmenopausal Bleeding
title_fullStr Diagnostic Strategies for Postmenopausal Bleeding
title_full_unstemmed Diagnostic Strategies for Postmenopausal Bleeding
title_short Diagnostic Strategies for Postmenopausal Bleeding
title_sort diagnostic strategies for postmenopausal bleeding
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821624/
https://www.ncbi.nlm.nih.gov/pubmed/20169169
http://dx.doi.org/10.1155/2010/850812
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