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Diagnostic Strategies for Postmenopausal Bleeding
Postmenopausal bleeding (PMB) is a common clinical problem. Patients with PMB have 10%–15% chance of having endometrial carcinoma and therefore the diagnostic workup is aimed at excluding malignancy. Patient characteristics can alter the probability of having endometrial carcinoma in patients with P...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821624/ https://www.ncbi.nlm.nih.gov/pubmed/20169169 http://dx.doi.org/10.1155/2010/850812 |
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author | Breijer, M. C. Timmermans, A. van Doorn, H. C. Mol, B. W. J. Opmeer, B. C. |
author_facet | Breijer, M. C. Timmermans, A. van Doorn, H. C. Mol, B. W. J. Opmeer, B. C. |
author_sort | Breijer, M. C. |
collection | PubMed |
description | Postmenopausal bleeding (PMB) is a common clinical problem. Patients with PMB have 10%–15% chance of having endometrial carcinoma and therefore the diagnostic workup is aimed at excluding malignancy. Patient characteristics can alter the probability of having endometrial carcinoma in patients with PMB; in certain groups of patients the incidence has been reported to be as high as 29%. Transvaginal sonography (TVS) is used as a first step in the diagnostic workup, but different authors have come to different conclusions assessing the accuracy of TVS for excluding endometrial carcinoma. Diagnostic procedures obtaining material for histological assessment (e.g., dilatation and curettage, hysteroscopy, and endometrial biopsy) can be more accurate but are also more invasive. The best diagnostic strategy for diagnosing endometrial carcinoma in patients with PMB still remains controversial. Future research should be focussed on achieving a higher accuracy of different diagnostic strategies. |
format | Text |
id | pubmed-2821624 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-28216242010-02-18 Diagnostic Strategies for Postmenopausal Bleeding Breijer, M. C. Timmermans, A. van Doorn, H. C. Mol, B. W. J. Opmeer, B. C. Obstet Gynecol Int Review Article Postmenopausal bleeding (PMB) is a common clinical problem. Patients with PMB have 10%–15% chance of having endometrial carcinoma and therefore the diagnostic workup is aimed at excluding malignancy. Patient characteristics can alter the probability of having endometrial carcinoma in patients with PMB; in certain groups of patients the incidence has been reported to be as high as 29%. Transvaginal sonography (TVS) is used as a first step in the diagnostic workup, but different authors have come to different conclusions assessing the accuracy of TVS for excluding endometrial carcinoma. Diagnostic procedures obtaining material for histological assessment (e.g., dilatation and curettage, hysteroscopy, and endometrial biopsy) can be more accurate but are also more invasive. The best diagnostic strategy for diagnosing endometrial carcinoma in patients with PMB still remains controversial. Future research should be focussed on achieving a higher accuracy of different diagnostic strategies. Hindawi Publishing Corporation 2010 2010-02-04 /pmc/articles/PMC2821624/ /pubmed/20169169 http://dx.doi.org/10.1155/2010/850812 Text en Copyright © 2010 M. C. Breijer et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Breijer, M. C. Timmermans, A. van Doorn, H. C. Mol, B. W. J. Opmeer, B. C. Diagnostic Strategies for Postmenopausal Bleeding |
title | Diagnostic Strategies for Postmenopausal Bleeding |
title_full | Diagnostic Strategies for Postmenopausal Bleeding |
title_fullStr | Diagnostic Strategies for Postmenopausal Bleeding |
title_full_unstemmed | Diagnostic Strategies for Postmenopausal Bleeding |
title_short | Diagnostic Strategies for Postmenopausal Bleeding |
title_sort | diagnostic strategies for postmenopausal bleeding |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821624/ https://www.ncbi.nlm.nih.gov/pubmed/20169169 http://dx.doi.org/10.1155/2010/850812 |
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