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Interactive real-time mapping and catheter ablation of the cavotricuspid isthmus guided by magnetic resonance imaging in a porcine model
AIMS: We investigated the feasibility of real-time magnetic resonance imaging (RTMRI) guided ablation of the cavotricuspid isthmus (CTI) by using a MRI-compatible ablation catheter. METHODS AND RESULTS: Cavotricuspid isthmus ablation was performed in an interventional RTMRI suite by using a novel 7...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821629/ https://www.ncbi.nlm.nih.gov/pubmed/19897495 http://dx.doi.org/10.1093/eurheartj/ehp460 |
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author | Hoffmann, Boris A. Koops, Andreas Rostock, Thomas Müllerleile, Kai Steven, Daniel Karst, Roman Steinke, Mark U. Drewitz, Imke Lund, Gunnar Koops, Susan Adam, Gerhard Willems, Stephan |
author_facet | Hoffmann, Boris A. Koops, Andreas Rostock, Thomas Müllerleile, Kai Steven, Daniel Karst, Roman Steinke, Mark U. Drewitz, Imke Lund, Gunnar Koops, Susan Adam, Gerhard Willems, Stephan |
author_sort | Hoffmann, Boris A. |
collection | PubMed |
description | AIMS: We investigated the feasibility of real-time magnetic resonance imaging (RTMRI) guided ablation of the cavotricuspid isthmus (CTI) by using a MRI-compatible ablation catheter. METHODS AND RESULTS: Cavotricuspid isthmus ablation was performed in an interventional RTMRI suite by using a novel 7 French, steerable, non-ferromagnetic ablation catheter in a porcine in vivo model (n = 20). The catheter was introduced and navigated by RTMRI visualization only. Catheter position and movement during manipulation were continuously visualized during the entire intervention. Two porcine prematurely died due to VT/VF. Anatomical completion of the CTI ablation line could be achieved after a mean of 6.3±3 RF pulses (RF energy: 1807±1016.4 Ws/RF pulse, temperature: 55.9±5.9°C) in n = 18 animals. In 15 of 18 procedures (83.3%) a complete CTI block was proven by conventional mapping in the electrophysiological (EP) lab. CONCLUSION: Completely non-fluoroscopic ablation guided by RTMRI using a steerable and non-ferromagnetic catheter is a promising novel technology in interventional electrophysiology. |
format | Text |
id | pubmed-2821629 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-28216292010-02-16 Interactive real-time mapping and catheter ablation of the cavotricuspid isthmus guided by magnetic resonance imaging in a porcine model Hoffmann, Boris A. Koops, Andreas Rostock, Thomas Müllerleile, Kai Steven, Daniel Karst, Roman Steinke, Mark U. Drewitz, Imke Lund, Gunnar Koops, Susan Adam, Gerhard Willems, Stephan Eur Heart J Clinical Research AIMS: We investigated the feasibility of real-time magnetic resonance imaging (RTMRI) guided ablation of the cavotricuspid isthmus (CTI) by using a MRI-compatible ablation catheter. METHODS AND RESULTS: Cavotricuspid isthmus ablation was performed in an interventional RTMRI suite by using a novel 7 French, steerable, non-ferromagnetic ablation catheter in a porcine in vivo model (n = 20). The catheter was introduced and navigated by RTMRI visualization only. Catheter position and movement during manipulation were continuously visualized during the entire intervention. Two porcine prematurely died due to VT/VF. Anatomical completion of the CTI ablation line could be achieved after a mean of 6.3±3 RF pulses (RF energy: 1807±1016.4 Ws/RF pulse, temperature: 55.9±5.9°C) in n = 18 animals. In 15 of 18 procedures (83.3%) a complete CTI block was proven by conventional mapping in the electrophysiological (EP) lab. CONCLUSION: Completely non-fluoroscopic ablation guided by RTMRI using a steerable and non-ferromagnetic catheter is a promising novel technology in interventional electrophysiology. Oxford University Press 2010-02 2009-11-05 /pmc/articles/PMC2821629/ /pubmed/19897495 http://dx.doi.org/10.1093/eurheartj/ehp460 Text en Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org http://creativecommons.org/licenses/by-nc/2.0/uk/ The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that the original authorship is properly and fully attributed; the Journal, Learned Society and Oxford University Press are attributed as the original place of publication with correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permissions@oxfordjournals.org. |
spellingShingle | Clinical Research Hoffmann, Boris A. Koops, Andreas Rostock, Thomas Müllerleile, Kai Steven, Daniel Karst, Roman Steinke, Mark U. Drewitz, Imke Lund, Gunnar Koops, Susan Adam, Gerhard Willems, Stephan Interactive real-time mapping and catheter ablation of the cavotricuspid isthmus guided by magnetic resonance imaging in a porcine model |
title | Interactive real-time mapping and catheter ablation of the cavotricuspid isthmus guided by magnetic resonance imaging in a porcine model |
title_full | Interactive real-time mapping and catheter ablation of the cavotricuspid isthmus guided by magnetic resonance imaging in a porcine model |
title_fullStr | Interactive real-time mapping and catheter ablation of the cavotricuspid isthmus guided by magnetic resonance imaging in a porcine model |
title_full_unstemmed | Interactive real-time mapping and catheter ablation of the cavotricuspid isthmus guided by magnetic resonance imaging in a porcine model |
title_short | Interactive real-time mapping and catheter ablation of the cavotricuspid isthmus guided by magnetic resonance imaging in a porcine model |
title_sort | interactive real-time mapping and catheter ablation of the cavotricuspid isthmus guided by magnetic resonance imaging in a porcine model |
topic | Clinical Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821629/ https://www.ncbi.nlm.nih.gov/pubmed/19897495 http://dx.doi.org/10.1093/eurheartj/ehp460 |
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