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An Overview of the Importance of Conformational Flexibility in Gene Regulation by the Transcription Factors

A number of proteins with intrinsically disordered (ID) regions/domains are reported to be found disproportionately higher in transcription factors. Available evidences suggest that presence of ID region/domain within a transcription factor plays an important role in its biological functions. These...

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Detalles Bibliográficos
Autores principales: Khan, Shagufta H., Kumar, Raj
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821642/
https://www.ncbi.nlm.nih.gov/pubmed/20169123
http://dx.doi.org/10.1155/2009/210485