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Differential Recognition of P. falciparum VAR2CSA Domains by Naturally Acquired Antibodies in Pregnant Women from a Malaria Endemic Area

BACKGROUND: Plasmodium falciparum infected red blood cells (iRBC) express variant surface antigens (VSA) of which VAR2CSA is involved in placental sequestration and causes pregnancy-associated malaria (PAM). Primigravidae are most susceptible to PAM whereas antibodies associated with protection are...

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Detalles Bibliográficos
Autores principales: Brolin, Kim J. M., Persson, Kristina E. M., Wahlgren, Mats, Rogerson, Stephen J., Chen, Qijun
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821912/
https://www.ncbi.nlm.nih.gov/pubmed/20169064
http://dx.doi.org/10.1371/journal.pone.0009230

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