Human parainfluenza virus type 2 V protein inhibits interferon production and signaling and is required for replication in non-human primates

In wild-type human parainfluenza virus type 2 (WT HPIV2), one gene (the P/V gene) encodes both the polymerase-associated phosphoprotein (P) and the accessory V protein. We generated a HPIV2 virus (rHPIV2-V(ko)) in which the P/V gene encodes only the P protein to examine the role of V in replication...

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Detalles Bibliográficos
Autores principales: Schaap-Nutt, Anne, D'Angelo, Christopher, Scull, Margaret A., Amaro-Carambot, Emerito, Nishio, Machiko, Pickles, Raymond J., Collins, Peter L., Murphy, Brian R., Schmidt, Alexander C.
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822077/
https://www.ncbi.nlm.nih.gov/pubmed/19969320
http://dx.doi.org/10.1016/j.virol.2009.11.018

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