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Detection of Aberrant p16(INK4A) Methylation in Sera of Patients with Liver Cirrhosis and Hepatocellular Carcinoma

Hepatocellular carcinomas (HCCs) show genomic alterations, including DNA rearrangements associated with HBV DNA integration, loss of heterozygosity, and chromosomal amplification. The genes most frequently involved are those encoding tumor suppressors. The p16(INK4A) tumor suppressor gene frequently...

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Detalles Bibliográficos
Autores principales:	Chu, Hyung Jun, Heo, Jeong, Seo, Soo Boon, Kim, Gwang Ha, Kang, Dae Hwan, Song, Geun Am, Cho, Mong, Yang, Ung Suk
Formato:	Texto
Lenguaje:	English
Publicado:	The Korean Academy of Medical Sciences 2004
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822270/ https://www.ncbi.nlm.nih.gov/pubmed/14966347 http://dx.doi.org/10.3346/jkms.2004.19.1.83

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