CLC-5 and KIF3B interact to facilitate CLC-5 plasma membrane expression, endocytosis, and microtubular transport: relevance to pathophysiology of Dent's disease

Renal tubular reabsorption is important for extracellular fluid homeostasis and much of this occurs via the receptor-mediated endocytic pathway. This pathway is disrupted in Dent’s disease, an X-linked renal tubular disorder that is characterized by low-molecular-weight proteinuria, hypercalciuria,...

Descripción completa

Detalles Bibliográficos
Autores principales: Reed, Anita A. C., Loh, Nellie Y., Terryn, Sara, Lippiat, Jonathan D., Partridge, Chris, Galvanovskis, Juris, Williams, Siân E., Jouret, Francois, Wu, Fiona T. F., Courtoy, Pierre J., Nesbit, M. Andrew, Rorsman, Patrik, Devuyst, Olivier, Ashcroft, Frances M., Thakker, Rajesh V.
Formato: Texto
Lenguaje:English
Publicado: American Physiological Society 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822520/
https://www.ncbi.nlm.nih.gov/pubmed/19940036
http://dx.doi.org/10.1152/ajprenal.00038.2009

Ejemplares similares

Ejemplares similares