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Statistics of protein-DNA binding and the total number of binding sites for a transcription factor in the mammalian genome

BACKGROUND: Transcription factor (TF)-DNA binding loci are explored by analyzing massive datasets generated with application of Chromatin Immuno-Precipitation (ChIP)-based high-throughput sequencing technologies. These datasets suffer from a bias in the information about binding loci availability, s...

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Detalles Bibliográficos
Autores principales: Kuznetsov, Vladimir A, Singh, Onkar, Jenjaroenpun, Piroon
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822526/
https://www.ncbi.nlm.nih.gov/pubmed/20158869
http://dx.doi.org/10.1186/1471-2164-11-S1-S12