Bioinformatic search of plant microtubule-and cell cycle related serine-threonine protein kinases

A bioinformatic search was carried for plant homologues of human serine-threonine protein kinases involved in regulation of cell division and microtubule protein phosphorylation (SLK, PAK6, PAK7, MARK1, MAST2, TTBK1, TTBK2, AURKA, PLK1, PLK4 and PASK). A number of SLK, MAST2 and AURKA plant homologu...

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Autores principales: Karpov, Pavel A, Nadezhdina, Elena S, Yemets, Alla I, Matusov, Vadym G, Nyporko, Alexey Yu, Shashina, Nadezhda Yu, Blume, Yaroslav B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822528/
https://www.ncbi.nlm.nih.gov/pubmed/20158871
http://dx.doi.org/10.1186/1471-2164-11-S1-S14
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author Karpov, Pavel A
Nadezhdina, Elena S
Yemets, Alla I
Matusov, Vadym G
Nyporko, Alexey Yu
Shashina, Nadezhda Yu
Blume, Yaroslav B
author_facet Karpov, Pavel A
Nadezhdina, Elena S
Yemets, Alla I
Matusov, Vadym G
Nyporko, Alexey Yu
Shashina, Nadezhda Yu
Blume, Yaroslav B
author_sort Karpov, Pavel A
collection PubMed
description A bioinformatic search was carried for plant homologues of human serine-threonine protein kinases involved in regulation of cell division and microtubule protein phosphorylation (SLK, PAK6, PAK7, MARK1, MAST2, TTBK1, TTBK2, AURKA, PLK1, PLK4 and PASK). A number of SLK, MAST2 and AURKA plant homologues were identified. The closest identified homologue of human AURKA kinase was a protein of unknown function, A7PY12/GSVIVT00026259001 from Vitis vinifera (herein named as "STALK", Serine-Threonine Aurora-Like Kinase). Analysis of STALK's three-dimensional structure confirmed its relationship to the subgroup of AURKA-like protein kinases.
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spelling pubmed-28225282010-02-17 Bioinformatic search of plant microtubule-and cell cycle related serine-threonine protein kinases Karpov, Pavel A Nadezhdina, Elena S Yemets, Alla I Matusov, Vadym G Nyporko, Alexey Yu Shashina, Nadezhda Yu Blume, Yaroslav B BMC Genomics Research A bioinformatic search was carried for plant homologues of human serine-threonine protein kinases involved in regulation of cell division and microtubule protein phosphorylation (SLK, PAK6, PAK7, MARK1, MAST2, TTBK1, TTBK2, AURKA, PLK1, PLK4 and PASK). A number of SLK, MAST2 and AURKA plant homologues were identified. The closest identified homologue of human AURKA kinase was a protein of unknown function, A7PY12/GSVIVT00026259001 from Vitis vinifera (herein named as "STALK", Serine-Threonine Aurora-Like Kinase). Analysis of STALK's three-dimensional structure confirmed its relationship to the subgroup of AURKA-like protein kinases. BioMed Central 2010-02-10 /pmc/articles/PMC2822528/ /pubmed/20158871 http://dx.doi.org/10.1186/1471-2164-11-S1-S14 Text en Copyright ©2010 Karpov et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Karpov, Pavel A
Nadezhdina, Elena S
Yemets, Alla I
Matusov, Vadym G
Nyporko, Alexey Yu
Shashina, Nadezhda Yu
Blume, Yaroslav B
Bioinformatic search of plant microtubule-and cell cycle related serine-threonine protein kinases
title Bioinformatic search of plant microtubule-and cell cycle related serine-threonine protein kinases
title_full Bioinformatic search of plant microtubule-and cell cycle related serine-threonine protein kinases
title_fullStr Bioinformatic search of plant microtubule-and cell cycle related serine-threonine protein kinases
title_full_unstemmed Bioinformatic search of plant microtubule-and cell cycle related serine-threonine protein kinases
title_short Bioinformatic search of plant microtubule-and cell cycle related serine-threonine protein kinases
title_sort bioinformatic search of plant microtubule-and cell cycle related serine-threonine protein kinases
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822528/
https://www.ncbi.nlm.nih.gov/pubmed/20158871
http://dx.doi.org/10.1186/1471-2164-11-S1-S14
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