Brimonidine is neuroprotective against glutamate-induced neurotoxicity, oxidative stress, and hypoxia in purified rat retinal ganglion cells

PURPOSE: To investigate the neuroprotective effect of α2-adrenergic agonist brimonidine in the presence of glutamate-induced neurotoxicity, oxidative stress, and hypoxia on in vitro cultures of purified rat retinal ganglion cells (RGCs). METHODS: Purified RGC cultures were obtained from retinas of 6...

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Detalles Bibliográficos
Autores principales: Lee, Kelvin Yoon Chiang, Nakayama, Mao, Aihara, Makoto, Chen, Yi-Ning, Araie, Makoto
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822551/
https://www.ncbi.nlm.nih.gov/pubmed/20161817

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