IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

During T cell–dependent responses, B cells can either differentiate extrafollicularly into short-lived plasma cells or enter follicles to form germinal centers (GCs). Interactions with T follicular helper (Tfh) cells are required for GC formation and for selection of somatically mutated GC B cells....

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Detalles Bibliográficos
Autores principales: Linterman, Michelle A., Beaton, Laura, Yu, Di, Ramiscal, Roybel R., Srivastava, Monika, Hogan, Jennifer J., Verma, Naresh K., Smyth, Mark J., Rigby, Robert J., Vinuesa, Carola G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822609/
https://www.ncbi.nlm.nih.gov/pubmed/20142429
http://dx.doi.org/10.1084/jem.20091738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822609/
https://www.ncbi.nlm.nih.gov/pubmed/20142429
http://dx.doi.org/10.1084/jem.20091738

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