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Induction of IFN-αβ enables Listeria monocytogenes to suppress macrophage activation by IFN-γ

Production of type I interferon (IFN; IFN-αβ) increases host susceptibility to Listeria monocytogenes, whereas type II IFN (IFN-γ) activates macrophages to resist infection. We show that these opposing immunological effects of IFN-αβ and IFN-γ occur because of cross talk between the respective signa...

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Detalles Bibliográficos
Autores principales: Rayamajhi, Manira, Humann, Jessica, Penheiter, Kristi, Andreasen, Karl, Lenz, Laurel L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822610/
https://www.ncbi.nlm.nih.gov/pubmed/20123961
http://dx.doi.org/10.1084/jem.20091746