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Induction of IFN-αβ enables Listeria monocytogenes to suppress macrophage activation by IFN-γ
Production of type I interferon (IFN; IFN-αβ) increases host susceptibility to Listeria monocytogenes, whereas type II IFN (IFN-γ) activates macrophages to resist infection. We show that these opposing immunological effects of IFN-αβ and IFN-γ occur because of cross talk between the respective signa...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822610/ https://www.ncbi.nlm.nih.gov/pubmed/20123961 http://dx.doi.org/10.1084/jem.20091746 |