Natural killer receptors: the burden of a name

A population of cells that expresses the NK cell receptor NKp46 and produces interleukin (IL)-22 have recently attracted considerable attention. The identity of these cells is still the subject of speculation, being variably defined as a novel NK cell subset or as a population containing conventiona...

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Detalles Bibliográficos
Autores principales: Veiga-Fernandes, Henrique, Kioussis, Dimitris, Coles, Mark
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822611/
https://www.ncbi.nlm.nih.gov/pubmed/20142428
http://dx.doi.org/10.1084/jem.20100105
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author Veiga-Fernandes, Henrique
Kioussis, Dimitris
Coles, Mark
author_facet Veiga-Fernandes, Henrique
Kioussis, Dimitris
Coles, Mark
author_sort Veiga-Fernandes, Henrique
collection PubMed
description A population of cells that expresses the NK cell receptor NKp46 and produces interleukin (IL)-22 have recently attracted considerable attention. The identity of these cells is still the subject of speculation, being variably defined as a novel NK cell subset or as a population containing conventional NK (cNK) cell precursors. In this issue, two studies shed light on this conundrum, demonstrating that NKp46(+) IL-22(+) cells and cNK cells belong to distinct lineages.
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spelling pubmed-28226112010-08-15 Natural killer receptors: the burden of a name Veiga-Fernandes, Henrique Kioussis, Dimitris Coles, Mark J Exp Med Commentary A population of cells that expresses the NK cell receptor NKp46 and produces interleukin (IL)-22 have recently attracted considerable attention. The identity of these cells is still the subject of speculation, being variably defined as a novel NK cell subset or as a population containing conventional NK (cNK) cell precursors. In this issue, two studies shed light on this conundrum, demonstrating that NKp46(+) IL-22(+) cells and cNK cells belong to distinct lineages. The Rockefeller University Press 2010-02-15 /pmc/articles/PMC2822611/ /pubmed/20142428 http://dx.doi.org/10.1084/jem.20100105 Text en © 2010 Veiga-Fernandes et al. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Commentary
Veiga-Fernandes, Henrique
Kioussis, Dimitris
Coles, Mark
Natural killer receptors: the burden of a name
title Natural killer receptors: the burden of a name
title_full Natural killer receptors: the burden of a name
title_fullStr Natural killer receptors: the burden of a name
title_full_unstemmed Natural killer receptors: the burden of a name
title_short Natural killer receptors: the burden of a name
title_sort natural killer receptors: the burden of a name
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822611/
https://www.ncbi.nlm.nih.gov/pubmed/20142428
http://dx.doi.org/10.1084/jem.20100105
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