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Cystatin E/M suppresses legumain activity and invasion of human melanoma
BACKGROUND: High activity of cysteine proteases such as legumain and the cathepsins have been shown to facilitate growth and invasion of a variety of tumor types. In breast cancer, several recent studies have indicated that loss of the cysteine protease inhibitor cystatin E/M leads to increased grow...
Autores principales: | Briggs, Jon J, Haugen, Mads H, Johansen, Harald T, Riker, Adam I, Abrahamson, Magnus, Fodstad, Øystein, Mælandsmo, Gunhild M, Solberg, Rigmor |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822816/ https://www.ncbi.nlm.nih.gov/pubmed/20074384 http://dx.doi.org/10.1186/1471-2407-10-17 |
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