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Impact of gene variants on sex-specific regulation of human Scavenger receptor class B type 1 (SR-BI) expression in liver and association with lipid levels in a population-based study

BACKGROUND: Several studies have noted that genetic variants of SCARB1, a lipoprotein receptor involved in reverse cholesterol transport, are associated with serum lipid levels in a sex-dependent fashion. However, the mechanism underlying this gene by sex interaction has not been explored. METHODS:...

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Detalles Bibliográficos
Autores principales: Chiba-Falek, Ornit, Nichols, Marshall, Suchindran, Sunil, Guyton, John, Ginsburg, Geoffrey S, Barrett-Connor, Elizabeth, McCarthy, Jeanette J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822818/
https://www.ncbi.nlm.nih.gov/pubmed/20085651
http://dx.doi.org/10.1186/1471-2350-11-9

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