Novel HIV-1 Knockdown Targets Identified by an Enriched Kinases/Phosphatases shRNA Library Using a Long-Term Iterative Screen in Jurkat T-Cells

HIV-1 is a complex retrovirus that uses host machinery to promote its replication. Understanding cellular proteins involved in the multistep process of HIV-1 infection may result in the discovery of more adapted and effective therapeutic targets. Kinases and phosphatases are a druggable class of pro...

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Detalles Bibliográficos
Autores principales: Rato, Sylvie, Maia, Sara, Brito, Paula M., Resende, Leonor, Pereira, Carina F., Moita, Catarina, Freitas, Rui P., Moniz-Pereira, José, Hacohen, Nir, Moita, Luis Ferreira, Goncalves, Joao
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822867/
https://www.ncbi.nlm.nih.gov/pubmed/20174665
http://dx.doi.org/10.1371/journal.pone.0009276

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