Increased Sensitivity of CD4+ T-Effector Cells to CD4+CD25+ Treg Suppression Compensates for Reduced Treg Number in Asymptomatic HIV-1 Infection

BACKGROUND: In HIV infection, uncontrolled immune activation and disease progression is attributed to declining CD4+CD25+FoxP3+ regulatory T-cell (Treg) numbers. However, qualitative aspects of Treg function in HIV infection, specifically the balance between Treg cell suppressive potency versus supp...

Descripción completa

Detalles Bibliográficos
Autores principales: Thorborn, Georgina, Pomeroy, Laura, Isohanni, Heidi, Perry, Melissa, Peters, Barry, Vyakarnam, Annapurna
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822868/
https://www.ncbi.nlm.nih.gov/pubmed/20174666
http://dx.doi.org/10.1371/journal.pone.0009254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822868/
https://www.ncbi.nlm.nih.gov/pubmed/20174666
http://dx.doi.org/10.1371/journal.pone.0009254

Ejemplares similares