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Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8(+) T cell responses to influenza

The question of which dendritic cells (DCs) respond to pulmonary antigens and cross-prime CD8(+) T cells remains controversial. We show that influenza-specific CD8(+) T cell priming is controlled by different DCs at different times after infection. Whereas early priming is controlled by both CD103(+...

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Detalles Bibliográficos
Autores principales: Ballesteros-Tato, André, León, Beatriz, Lund, Frances E., Randall, Troy D.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822886/
https://www.ncbi.nlm.nih.gov/pubmed/20098442
http://dx.doi.org/10.1038/ni.1838