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Two novel human anti-ErbB2 immunoagents are active on trastuzumab-resistant tumours

BACKGROUND: Overexpression of ErbB2 receptor in breast cancer is associated with disease progression and poor prognosis. Trastuzumab, the only humanised anti-ErbB2 antibody currently used in breast cancer, has proven to be effective; however, a relevant problem for clinical practice is that a high f...

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Detalles Bibliográficos
Autores principales:	Gelardi, T, Damiano, V, Rosa, R, Bianco, R, Cozzolino, R, Tortora, G, Laccetti, P, D'Alessio, G, De Lorenzo, C
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822937/ https://www.ncbi.nlm.nih.gov/pubmed/20051960 http://dx.doi.org/10.1038/sj.bjc.6605499

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