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On finding poorly translated codons based on their usage frequency
Long stretches of “rare” codons are known to severely inhibit the efficiency of translation. Understanding the distribution of such rare codons is of critical importance in improving the efficiency of heterologous gene expression systems. Accurate estimates of codon usage take the abundance of each...
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| Formato: | Texto |
| Lenguaje: | English |
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Biomedical Informatics
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823382/ https://www.ncbi.nlm.nih.gov/pubmed/20198170 |