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Mammalian SUN Protein Interaction Networks at the Inner Nuclear Membrane and Their Role in Laminopathy Disease Processes

The nuclear envelope (NE) LINC complex, in mammals comprised of SUN domain and nesprin proteins, provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity. SUN1 and SUN2 interact with lamin A, but lamin A is only requ...

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Detalles Bibliográficos
Autores principales:	Haque, Farhana, Mazzeo, Daniela, Patel, Jennifer T., Smallwood, Dawn T., Ellis, Juliet A., Shanahan, Catherine M., Shackleton, Sue
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2010
Materias:	Molecular Basis of Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823409/ https://www.ncbi.nlm.nih.gov/pubmed/19933576 http://dx.doi.org/10.1074/jbc.M109.071910

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