Annexin-II, DNA, and Histones Serve as Factor H Ligands on the Surface of Apoptotic Cells

Apoptotic cells are opsonized by complement components such as C1q and C3b, which increases their susceptibility to phagocytosis. Soluble complement inhibitors such as factor H (fH) also recognize apoptotic cells to minimize the pro-inflammatory effects of downstream complement activation. We used f...

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Detalles Bibliográficos
Autores principales: Leffler, Jonatan, Herbert, Andrew P., Norström, Eva, Schmidt, Christoph Q., Barlow, Paul N., Blom, Anna M., Martin, Myriam
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Molecular Basis of Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823518/
https://www.ncbi.nlm.nih.gov/pubmed/19951950
http://dx.doi.org/10.1074/jbc.M109.045427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823518/
https://www.ncbi.nlm.nih.gov/pubmed/19951950
http://dx.doi.org/10.1074/jbc.M109.045427

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