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Cell-Cell Contact Formation Governs Ca(2+) Signaling by TRPC4 in the Vascular Endothelium: EVIDENCE FOR A REGULATORY TRPC4-β-CATENIN INTERACTION

TRPC4 is well recognized as a prominent cation channel in the vascular endothelium, but its contribution to agonist-induced endothelial Ca(2+) entry is still a matter of controversy. Here we report that the cellular targeting and Ca(2+) signaling function of TRPC4 is determined by the state of cell-...

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Detalles Bibliográficos
Autores principales:	Graziani, Annarita, Poteser, Michael, Heupel, Wolfgang-Moritz, Schleifer, Hannes, Krenn, Martin, Drenckhahn, Detlev, Romanin, Christoph, Baumgartner, Werner, Groschner, Klaus
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2010
Materias:	Mechanisms of Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823560/ https://www.ncbi.nlm.nih.gov/pubmed/19996314 http://dx.doi.org/10.1074/jbc.M109.060301

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